Amxol Syrup contains Ambroxol Hydrochloride, a mucolytic agent used to relieve symptoms of respiratory conditions by thinning and loosening mucus, making it easier to expel.

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Indications:

Amxol Syrup is indicated for:

1. Productive Cough associated with:
   • Acute and chronic bronchitis.
   • Pneumonia.
   • Chronic obstructive pulmonary disease (COPD).
   • Asthma with mucus overproduction.
   • Bronchiectasis.
2. Respiratory Infections:
   • Helps clear mucus buildup in infections affecting the respiratory tract.

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Dosage and Administration:

General Dosage Guidelines:

• Adults and adolescents (12 years and older):
  10 mL (2 teaspoons) 2–3 times daily.
• Children (6–12 years):
  5 mL (1 teaspoon) 2–3 times daily.
• Children (2–5 years):
  2.5 mL (½ teaspoon) 2–3 times daily.
• Children under 2 years:
  2.5 mL (½ teaspoon) twice daily (under medical supervision).

Take after meals to minimize the risk of gastric irritation. Follow the exact dosage as prescribed by your healthcare provider.

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Mechanism of Action:

Ambroxol acts as a mucolytic:

• It enhances the production of serous mucus in the respiratory tract, breaking down thick and sticky mucus.
• Improves mucociliary clearance, facilitating the removal of mucus from the airways.

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Precautions:

1. Gastrointestinal Disorders:
   • Use cautiously in patients with a history of gastric ulcers.
2. Pregnancy and Breastfeeding:
   • Avoid use during the first trimester of pregnancy unless prescribed. Use with caution during breastfeeding.
3. Allergic Reactions:
   • Discontinue use if any signs of hypersensitivity occur.
4. Severe Respiratory Conditions:
   • Monitor patients with severe respiratory insufficiency closely.

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Side Effects:

Common side effects:

• Nausea or stomach discomfort.
• Diarrhea.
• Dry mouth or throat.

Rare but serious side effects (seek medical attention):

• Allergic reactions (rash, itching, or difficulty breathing).
• Severe skin reactions like Stevens-Johnson Syndrome or toxic epidermal necrolysis (extremely rare).

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Drug Interactions:

• Antitussives (e.g., Codeine): Avoid concurrent use as they suppress the cough reflex, potentially leading to mucus retention.
• Antibiotics (e.g., Amoxicillin, Cefuroxime): Ambroxol may enhance antibiotic penetration into bronchial secretions, improving their efficacy.

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Storage:

• Store at room temperature (15°C–30°C).
• Protect from light and moisture.
• Keep out of reach of children.